TY - JOUR AU - WAN-NADILAH, WAN AHMAD AU - GHANI, DAILAMI ABDUL AU - ABD JALIL, MUHAMMAD SYAFIQ AU - ALI, ABDUL MANAF AU - MAMAT, WAN NUR AMALINA WAN AU - MAHMOD, NOR HASIMA PY - 2020/12/25 Y2 - 2024/03/29 TI - EFFECTS OF DRYING METHODS AND SOLVENTS ON PHENOLIC AND FLAVONOIDS CONTENT, DPPH RADICAL SCAVENGING AND -GLUCOSIDASE ACTIVITIES OF Aquilaria LEAVES EXTRACT JF - Malaysian Applied Biology JA - MAB VL - 49 IS - 4 SE - Research Articles DO - 10.55230/mabjournal.v49i4.1619 UR - https://jms.mabjournal.com/index.php/mab/article/view/1619 SP - 201-205 AB - <p><em>Aquilaria </em>is a multipurpose plant with high commercial and medicinal values. The present study aimed to evaluate the effects of drying methods and extraction solvents on the phenolic and flavonoids content in <em>A. malaccensis </em>(AMA), <em>A. subintegra </em>(ASU), and <em>A. sinensis </em>(ASI). Leaf samples were either Air-Dried (AD) or Oven-Dried (OD) and extracted using 100% Ethanol (EE100), 70% ethanol (EE70), aqueous (AE), and hexane (HE). There was a significant difference (<em>p&lt;</em>0.05) between the drying methods and the extracting solvents. The OD in AMA leaf samples gave the highest values of total phenolic compounds (TPC) (52.98 – 85.15 mg GAE/gm) and total flavonoid compounds (TFC) (2180.97 – 3733.45 QUE ppm). The highest DPPH radical scavenging was observed in OD-EE70-AMA with the IC<sub>50</sub> value of 33.60 µg/mL. Meanwhile, OD-EE100-AMA gave the lowest IC<sub>50</sub> value (0.13 µg/mL) in the a-glucosidase assay, followed by OD-EE70-AMA with IC<sub>50</sub> value 0.69 µg/mL with no significant differences among them. OD-EE70-AMA was found to have a higher content of TPC and TFC with the most potent DPPH scavenging and a-glucosidase inhibition activities. A strong positive correlation was reported between bioassays and TPC or TFC, hence indicating that AMA leaf used in this study might have the potential as a natural antioxidant and an antidiabetic agent.</p> ER -